Sodium Hydroxide Solutions for Pharma & Food Sectors

SODIUM HYDROXIDE SOLUTIONS FOR BIOPHARMA, PHARMA AND FOOD SECTORS

For over four decades, Micro-Bio has been a trusted manufacturer of high-purity Sodium Hydroxide (NaOH) solutions.

Produced at our cGMP and ISO-certified facility in Fermoy, Co. Cork, our Sodium Hydroxide is manufactured directly from raw materials through our electrolytic membrane-cell process, not from pellets.

This ensures total control over quality, consistency, and traceability from source to delivery.

As with all Micro-Bio products, our Sodium Hydroxide solutions benefit from the same manufacturing integrity, supply-chain security and regulatory compliance that come from sourcing directly from the raw-material manufacturer.

Learn more about the advantages of sourcing directly from Micro-Bio below.

Applications

Sodium Hydroxide is a critical raw material across multiple stages of biopharma, pharmaceutical, and dairy manufacturing, including:

Cleaning and sanitisation (CIP systems)

Sodium hydroxide is widely used in CIP systems thanks to its strong alkaline action, which efficiently breaks down organic residues and removes process contaminants. It plays a key role in cleaning bioreactors, mixing vessels, and other production equipment, and is also applied as a disinfectant for cleanroom surfaces and associated apparatus.
Chromatography and protein purification

Chromatography is a widely used technique for protein purification in biopharmaceutical manufacturing. During this process, sodium hydroxide is commonly applied for column cleaning and sanitisation between cycles, helping to remove residual proteins and impurities and maintain consistent purification performance.
Buffer production and pH adjustment

Sodium hydroxide provides strong buffering capacity and is widely used for pH adjustment across a range of life sciences production processes, supporting consistent buffer preparation and reliable process performance.
Resin cleaning and storage

Chromatography resins are routinely cleaned and stored between purification runs to maintain performance. Sodium hydroxide is used in these steps to remove bound proteins and impurities, as well as to sanitise the resin, helping ensure consistent results in subsequent purification cycles.
Water treatment and neutralisation processes

Sodium hydroxide is widely used in water treatment to adjust pH and neutralise acidic process streams, helping to maintain stable operating conditions. It is also applied to treat waste media and process effluents, supporting safe handling and compliant disposal.

The advantages of sourcing hydroxide solutions directly from Micro-Bio include:

Product Quality: All Micro-Bio products are manufactured using our electrolytic membrane cell process, producing high-purity, cGMP-grade chemical solutions.
Quality Assurance: We operate to ISO 9001:2015 standards and cGMP controls, maintaining full oversight from raw material sourcing through manufacturing, storage, filling, and delivery. Our in-house laboratory tests every batch to multi-compendial standards for full compliance.
Supply Chain Security: Customers benefit from a reliable, local source of high-purity products with reduced lead times and no dependency on intermediaries, ensuring supply continuity and compliance with cGMP sourcing guidelines.
Technical Support: Our experienced team provides expert guidance on product selection, handling, and storage to help customers maintain safe and efficient operations.
Traceability: Every production stage is documented, providing complete visibility from origin to delivery and meeting stringent regulatory and audit requirements.
Regulatory Compliance: All products are manufactured under cGMP and ISO-certified systems, ensuring alignment with industry and regulatory standards.
Flexible Product Offering: We provide bespoke concentrations, tailored packaging, and fast turnaround times, adapting to each customer’s process and scale.

High Purity Sodium Hydroxide Solutions – Documentation

The use of Sodium Hydroxide in biopharmaceutical, pharmaceutical and food manufacturing processes is crucial for ensuring high-quality and consistent products.

We offer Sodium Hydroxide solutions produced under cGMP and ISO: 9001:2015 accredited quality system. All safety data sheets and other documentation relating to these products are available on request.

Product Information and Documentation

Micro-Bio offers Sodium Hydroxide solutions produced under a cGMP and ISO 9001:2015 accredited quality system.

Safety Data Sheets (SDS), Certificates of Analysis (CoA), and other supporting documentation are available on request.

We manufacture Sodium Hydroxide solutions in concentrations ranging from 0.5 N to 50 %, supplied in bulk tankers, IBCs, and containers from 5 L to 200 L.
Custom concentrations and packaging formats are available to meet specific process requirements.